RNA Details
Disease Name
conjunctival fibrosis
Tissue
eye
RNA Symbol
mir-143
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
RT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
Transforming Growth Factor-beta1-induced Human Subconjunctival Fibrosis is Mediated by MicroRNA 143/145 Expression
Year
2019
Function
"Tgf-beta1-induced human subconjunctival fibrosis was mediated by the expression of microrna 143;145, Mainly via smad-independent pathways. Inhibition of tgf-beta1-induced microrna 143;145 Expression in htfs might represent a novel strategy to prevent subconjunctival fibrosis."